About me

Hi! My name is Jeroen Verharen and I’m a behavioral neuroscientist interested in how the brain processes rewarding and aversive experiences. Using different neural circuit dissection tools (calcium imaging, pharmacology, anatomical tracing and chemogenetics), I study how the dopamine system is involved in shaping such experiences into adaptive behavior.

Curriculum Vitae

2019 – now: Postdoc (Rubicon fellow)
University of California, Berkeley, United States
Advisor: Dr. Stephan Lammel

2014 – 2018: Ph.D.
Utrecht University Medical Center, Netherlands
Advisors: Dr. Roger Adan, Dr. Louk Vanderschuren
Download thesis

2012 – 2014: M.Sc.
VU University Amsterdam, Netherlands
Cum laude distinction

2008 – 2011: B.Sc. Medicine
VU University Amsterdam, Netherlands

Current projects

As a postdoc in the Lammel lab, I’m currently working on two projects:
(1) The neurocomputational basis of the optimistic interpretation bias in rodents
(2) The topographic organization of reward processing in the striatum

If you want to know more or if you’re interested in collaborating, shoot me an email!

Publications

Google Scholar | PubMed


2020

Verharen JPH, Luijendijk MCM, Vanderschuren LJMJ, Adan RAH. Dopaminergic contributions to behavioral control under threat of punishment in rats. Psychopharmacology. (2020)
Online | PDF | Code

Verharen JPH, De Jong JW, Lammel S. Dopaminergic control over the tripartite synapse. Neuron. (2020)
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Verharen JPH, Zhu Y, Lammel S. Aversion Hot Spots in the Dopamine System. Current Opinion in Neurobiology. (2020)
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Verharen JPH, den Ouden HEM, Adan RAH, Vanderschuren LJMJ. Modulation of value-based decision making behavior by subregions of the rat prefrontal cortex. Psychopharmacology. (2020)
Online | PDF | Data and code


2019

Verharen JPH, Danner UN, Schröder S, Aarts E, van Elburg AA, Adan RAH. Insensitivity to Losses: A Core Feature in Patients With Anorexia Nervosa? Biological Psychiatry Cognitive Neuroscience and Neuroimaging. (2019)
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Verharen JPH, Adan RAH, Vanderschuren LJMJ. Differential contributions of striatal dopamine D1 and D2 receptors to component processes of value-based decision making. Neuropsychopharmacology. (2019)
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Verharen JPH, van den Heuvel MW, Luijendijk MCM, Vanderschuren LJMJ, Adan RAH. Corticolimbic Mechanisms of Behavioral Inhibition under Threat of Punishment. The Journal of Neuroscience. (2019)
Online | PDF | Code |

Verharen JPH, Adan RAH, Vanderschuren LJMJ. How Reward and Aversion Shape Motivation and Decision Making: A Computational Account. Neuroscientist. (2019)
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Verharen JPH, Roelofs TJM, Menting-Henry S, Luijendijk MCM, Vanderschuren LJMJ, Adan RAH. Limbic control over the homeostatic need for sodium. Scientific Reports. (2019)
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Verharen JPH, Kentrop J, Vanderschuren LJMJ, Adan RAH. Reinforcement learning across the rat estrous cycle. Psychoneuroendocrinology. (2019)
Online | PDF | Data


2018

Verharen JPH, De Jong JW, Roelofs TJM, Huffels CFM, van Zessen R, Luijendijk MCM, Hamelink R, Willuhn I, den Ouden HEM, van der Plasse G, Adan RAH, Vanderschuren LJMJ. A neuronal mechanism underlying decision-making deficits during hyperdopaminergic states. Nature Communications. (2018)
Online | PDF | YouTube


2017

Roelofs TJM, Verharen JPH, van Tilborg GAF, Boekhoudt L, van der Toorn A, de Jong JW, Luijendijk MCM, Otte WM, Adan RAH, Dijkhuizen RM. A novel approach to map induced activation of neuronal networks using chemogenetics and functional neuroimaging in rats: A proof-of-concept study on the mesocorticolimbic system. Neuroimage. (2017)
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Preprints

Omrani H, Bijlsma A, Spoelder M, Verharen JPH, Bauer L, Cornelis C, van Dorland R, Vanderschuren LJMJ, Wierenga, CJ. An altered cognitive strategy associated with reduction of synaptic inhibition in the prefrontal cortex after social play deprivation in rats. bioRxiv. (2020)
Online

Wichmann R, Vander Weele CM, Yosafat AS, Schut EHS, Verharen JPH, Sridharma S, Siciliano CA, Izadmehr EM, Farris KM, Wildes CP, Kimchi EY, Tye KM. Acute stress induces long-lasting alterations in the dopaminergic system of female mice. bioRxiv. (2017)
Online

Contact

Jeroen P.H. Verharen, PhD
Life Science Addition
Berkeley, CA 94720
United States

undefined jeroenverharen@berkeley.edu